15 GPx links two GSH molecules through a disulfide bridge to form GSSG and, during this process, H 2 O 2 is reduced to water and lipid hydroperoxides to their corresponding alcohols
It is important to note that there is no definitive scientific consensus that these drugs directly cause pancreatitis, and the absolute risk appears to be low based on clinical trial data
*Correspondence: Haike Antelmann, [email protected] These authors have contributed equally to this work This article was submitted to Virology, a section of the journal Frontiers in Microbiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
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While the metabolic impacts of these medications are well documented, interest is now growing in their potential effects beyond glucose control, including neuropsychiatric outcomes